Ford E-350 / E-450 2021-2022 Fuse Box Diagram – Location, Fuses & Relay Assignments

This article covers the fourth generation Ford E-Series (fourth refresh), available from 2021. Here you will find the Ford E-Series 2021 and 2022 (Econoline, E-350, E-450) fuse box diagrams, information on the location of the fuse boxes in the car and the assignment of each fuse (fuse layout).

Passenger Compartment Fuse Box

Fuse Box Location

The fuse panel is to the left-hand side of the brake pedal and mounted onto the lower left-hand cowl panel. Remove the fuse panel cover to access the fuses.

Fuse Box Diagram

Assignment of the fuses in the instrument panel (2021-2022)

№	Rating	Protected Component
1	—	Not used.
2	10 A	Left-hand front and right-hand front door lock switch (cutaway). Inverter (cutaway). Connector (stripped chassis).
3	7.5 A	Power mirror switch (cutaway). Not used (stripped chassis).
4	20 A	2021: Trailer brake control.
5	20 A	Not used (spare).
6	10 A	Not used (spare).
7	10 A	Not used (spare).
8	10 A	Not used (spare).
9	10 A / 5 A	Not used (spare).
10	—	Not used.
11	—	Not used.
12	7.5 A	Smart datalink connector. Enterprise wired-in-device (2021).
13	7.5 A	Cluster. Steering column control module.
14	15 A	Not used (spare).
15	15 A	Not used (spare).
16	—	Not used.
17	7.5 A	Not used.
18	7.5 A	2021: Climate mode switch. 2022: R/S feed for Front blend actuator/climate mode switch (cutaway). R/S feed to strip chassis connector (stripped chassis).
19	5 A	Radio transceiver module and telematics control unit.
20	5 A	Ignition switch.
21	5 A	Not used.
22	5 A	Body builder B-pillar connector (cutaway). Not used (stripped chassis).
23	30 A	Not used (spare).
24	30 A	Not used (spare).
25	20 A	Not used (spare).
26	30 A	Not used (spare).
27	30 A	Not used (spare).
28	30 A	Not used (spare).
29	15 A	Upfitter interface module (cutaway). Not used (stripped chassis).
30	5 A	Not used (spare).
31	10 A	Smart datalink connector.
32	20 A	Radio.
33	—	Not used.
34	30 A	Not used (spare).
35	5 A	Tow haul switch.
36	15 A	Rearview mirror (cutaway). Rearview camera (cutaway) (2021). Camera lane departure (cutaway) (2022). Not used (stripped chassis).
37	20 A	Not used (spare).
38	30 A	Rear window switches and motors (cutaway). Not used (stripped chassis).

Engine Compartment Fuse Box

Fuse Box Location

Fuse Box Diagram

Assignment of the fuses in the engine compartment (2021-2022)

№	Rating	Protected Component
1	20 A	Horn.
2	50 A	Blower motor.
3	—	Not used.
4	30 A	Starter relay.
5	20 A	Not used (spare).
6	20 A	Upfitter relay 4 (cutaway). Not used (spare) (stripped chassis).
8	—	Not used.
10	—	Not used.
12	20 A	Power point 4.
13	10 A	Yaw sensor (stripped chassis). Not used (spare) (cutaway).
14	10 A	Forward looking radar (cutaway). Not used (spare) (stripped chassis).
15	—	Not used.
16	—	Not used.
17	10 A	Powertrain control module run/start feed.
18	10 A	Anti-lock brake system run/start feed.
19	—	Not used.
20	30 A	Wiper power.
21	—	Not used.
22	10 A	Wiper module (stripped chassis). Not used (spare) (cutaway).
23	—	Not used.
24	40 A	Body control module – run power in feed 2.
25	50 A	Body control module – run power in feed 1.
26	—	Not used.
27	20 A	Body builder frame connector.
28	—	Not used.
29	10 A	B+ power 12 V(special order vehicle).
30	30 A	Power driver seat (cutaway). Not used (spare) (stripped chassis).
31	—	Not used.
32	20 A	Vehicle power 1.
33	20 A	Vehicle power 2.
34	10 A	Vehicle power 3.
35	20 A	Vehicle power 4.
36	—	Not used.
37	—	Not used.
38	10 A	Washer relay (stripped chassis). Not used (spare) (cutaway).
39	—	Not used.
41	30 A	Trailer brake control connector.
43	30 A	Instrument panel connector (stripped chassis). Not used (spare) (cutaway).
45	—	Not used.
46	10 A	A/C clutch.
47	40 A	Upfitter relay 1 (cutaway). Not used (spare) (stripped chassis).
48	—	Not used.
49	30 A	Pump electronics module.
50	15 A	Injectors.
51	20 A	Power point 1.
52	50 A	Aux AC Prep on B-pillar vehicle connector (cutaway). Not used (spare) (stripped chassis). Power at all times (PAAT)
53	30 A	Trailer tow park lamps.
54	40 A	Upfitter 2 relay (cutaway). Not used (spare) (stripped chassis). R/S feed on instrument panel connector (2022).
55	20 A	Upfitter 3 relay (cutaway). Not used (spare) (stripped chassis).
56	20 A	Power point 2 prep B-pillar connector.
58	5 A	USB smart charger.
59	10 A	Park lamps 1 (special order vehicle).
60	—	Not used.
61	—	Not used.
62	—	Not used.
63	—	Not used.
64	—	Not used.
65	—	Not used.
66	—	Not used.
67	—	Not used.
69	—	Not used.
70	40 A	Inverter.
71	30 A	Anti-lock brake system valves.
72	10 A	Brake on and off switch.
73	—	Not used.
74	—	Not used.
75	—	Not used.
76	60 A	Anti-lock brake system pump.
77	30 A	Voltage quality module power – body control module.
78	10 A	Trailer tow stop lamps.
79	—	Not used.
80	10 A	Trailer tow backup lamps.
81	—	Not used.
82	5 A	Run/start fuse – upfitter relays (cutaway) (2021). B+ fuse – upfitter relay (2021). Upfitter switch (factory location for ignition power) (2022)
83	5 A	2022: Upfitter switch (optional location for power at all times).
84	—	Not used.
85	—	Not used.
86	—	Not used.
87	—	Not used.
88	—	Not used.
89	—	Not used.
91	40 A	Hot at all times (HAAT) / B+PWR on B-Pillar connector (cutaway). Battery Power on instrument panel connector (stripped chassis).
93	10 A	Park lamps 3 (special order vehicle).
94	10 A	Park lamps 2 (special order vehicle).
95	20 A	Stop lamp relay.
96	—	Not used.
97	50 A	Engine. B-pillar vehicle connector. Instrument panel.
98	30 A	Trailer tow battery charge.
99	40 A	2021: Instrument panel connector. 2022: Upfitter 2 relay (cutaway) / Not used (spare) (stripped chassis).
100	—	Not used.
101	—	Not used.
102	—	Not used.
103	—	Not used.
104	—	Not used.
105	15 A	Trailer tow right-hand and left-hand stop and direction indicator relay power.
R02	—	Powertrain control module. Power relay.
R05	—	Not used.